Comprehensive Analysis of the Health Benefits of Safflower

Safflower, scientifically known as Carthamus tinctorius, is a plant belonging to the Asteraceae family. Safflower oil, made from safflower seeds, is rich in unsaturated fatty acids and is available in many supermarkets. Moreover, the flowers and seeds of safflower have been used in traditional Chinese and Iranian medicine for centuries.

Health Benefits of Safflower


Every part of the safflower plant offers health - promoting properties, ranging from improving heart health to enhancing blood circulation. Some research has provided strong support for the positive effects of safflower on heart health.

Helps Lower Cholesterol


High - oleic safflower oil is an excellent source of monounsaturated fatty acids. Especially when used to replace saturated fats, it can effectively reduce low - density lipoprotein cholesterol. High cholesterol can lead to atherosclerosis, where plaque accumulates inside the arteries. This, in turn, increases the risk of heart disease and stroke. Changing dietary habits, such as replacing oils rich in saturated fats (like palm oil) with foods rich in monounsaturated fats (such as high - oleic safflower oil), can help prevent high cholesterol. Here, the "high - oleic" characteristic is crucial because this type of safflower oil contains a high level of oleic acid, a monounsaturated omega - 9 fatty acid.

May Improve Heart Health


In addition to helping improve cholesterol levels, safflower also promotes other aspects of heart health. Crocin, a flavonoid in safflower, has antioxidant and anti - inflammatory properties. A study has shown that crocin A may help prevent further health complications after a heart attack caused by elevated angiotensin II (a hormone that constricts blood vessels). However, more research is needed before safflower can be regarded as a reliable treatment for improving cardiovascular health.

May Improve Blood Flow


One of the main uses of safflower in traditional Chinese medicine is to improve blood circulation, and some research has corroborated this claimed benefit. Some studies have found that safflower helps lower high blood pressure, enhance blood flow, and dilate arteries. Therefore, safflower has the potential to be a promising treatment for stroke. Some research indicates that compared with Ginkgo biloba or dipyridamole, hydroxysafflor yellow A (an active compound in safflower) can improve neurological function after acute ischemic stroke, which is caused by reduced cerebral blood flow leading to brain cell damage. However, to further confirm these benefits and determine whether safflower is indeed a viable treatment for acute ischemic stroke, larger - scale and more up - to - date randomized controlled trials on humans are necessary.

May Improve Blood Sugar


Some research suggests that safflower may contribute to better blood sugar control. A study found that safflower injections can assist in treating diabetes due to the plant's effects on blood vessels. The active ingredients in safflower, crocin and hydroxysafflor yellow A, can help reduce oxidative stress and inflammation, which may be beneficial for improving blood sugar levels in diabetes patients.

How to Use Safflower


Safflower resembles thistle, but its flowers are yellow and orange. Safflower seeds are particularly important as they can be used to make safflower oil, a common cooking oil. The most common monounsaturated safflower oil is suitable for frying or baking, while the less common polyunsaturated safflower oil is not suitable for heating and is more suitable for making salad dressings. This is because the chemical bonds of polyunsaturated fatty acids are weaker, making them more prone to oxidation. Oxidized oil not only has a worse taste but may also cause oxidative stress in the body, which is associated with cardiovascular diseases (CVD), cancer, and neurodegenerative diseases.


Safflower is sometimes used to make tea for therapeutic purposes. In traditional Persian textbooks, safflower and its seeds are reported to have a laxative effect. However, most of the current research has been conducted on animals or in test - tubes, so more human - based research is needed to confirm the medicinal value of safflower and to determine the most effective way to use it.


Finally, Liposyn, a type of safflower oil, is commonly used to provide dietary fat through total parenteral nutrition (TPN), a feeding method that directly injects nutrients into the veins to bypass the gastrointestinal tract. This is usually used in a hospital setting when a patient cannot eat through the mouth or by tube feeding. In addition, traditional Chinese medicine sometimes uses safflower oil in injection form to promote blood circulation.

Dosage


Currently, there is no fixed dosage for safflower. However, safflower seed oil increases dietary fat intake. The Dietary Guidelines for Americans recommend that 25 - 30% of calorie intake should come from dietary fat. This may include safflower oil and other dietary fat sources such as nuts, butter, avocados, cream, fatty meats, and other oils. Since unsaturated fats are more beneficial to heart health, the Dietary Guidelines for Americans suggest limiting saturated fat intake to less than 10% of total calories. Safflower oil, as a source of unsaturated fat, can be used to replace saturated fats like palm oil. However, research on the safflower flower itself is insufficient to determine a recommended dosage.

Is Safflower Safe?


Generally, consuming safflower seed oil is safe, especially when used in moderation like other cooking oils. However, excessive consumption of safflower seed oil may have adverse effects. Consuming the flower during pregnancy may be unsafe. Some animal studies have found that it can disrupt the embryos of pregnant mice, while human - based research is limited. Similarly, there is little research on the safety of taking safflower during breastfeeding. Therefore, if you are breastfeeding, it is advisable to avoid taking safflower in herbal form. Moderate use of safflower seed oil during pregnancy or breastfeeding may be safe.


In addition, safflower may slow down blood clotting, especially in injection form. If you have a bleeding disorder or are about to undergo surgery, you need to be cautious when taking safflower. Also, safflower may cause allergic reactions, especially in people who are allergic to other plants in the Asteraceae family, such as ragweed, daisies, marigolds, etc.

Potential Drug Interactions


If you are taking anticoagulants or antidiabetic drugs, you may need to limit your intake of safflower. Since safflower has been proven to prevent blood clotting, using it in combination with anticoagulants like warfarin (Coumadin) can be dangerous. Moreover, there is evidence that safflower oil can improve blood sugar control in type 2 diabetes patients. Therefore, if you are taking antidiabetic drugs, using safflower oil simultaneously may lead to hypoglycemia (low blood sugar). If you are taking any of these drugs, consult a healthcare provider before taking safflower, especially in large doses.

What to Look For


Safflower is a bushy herb similar to thistle. Sometimes, its oval - shaped leaves are spiny, but there are also spineless varieties. The flowers themselves are bright yellow, orange, and red. You can purchase safflower petals from some retailers, usually those selling herbal teas. Safflower oil is more easily accessible and can be found in the cooking oil section of most grocery stores.

What Happens if You Consume Too Much Safflower?


Like any other nutrient, safflower oil can also be over - consumed. Safflower oil is a source of heart - healthy fats, but dietary fat generally only accounts for 25 - 30% of calorie intake. To maintain a balanced and healthy diet, ensure the intake of carbohydrates and proteins. In traditional Iranian medicine, experts recommend a maximum daily intake of 20 - 40 grams of safflower seeds and 3 grams of safflower. However, in Western medicine, there is not enough research to determine whether there is a safe upper limit and what that limit might be.

Side Effects of Safflower


Safflower oil is generally well - tolerated when consumed as part of the daily diet or injected intravenously in a hospital setting. However, some people may have an allergic reaction to safflower, especially those allergic to plants in the same family, such as ragweed. Symptoms of ragweed allergy include sneezing, runny nose, nasal congestion, headache, eye inflammation, and itchy throat. In rare cases, excessive consumption of safflower oil can lead to liver failure. Currently, only seven such cases have been reported, and the dosage and duration of safflower oil intake are unknown.

Quick Review


Safflower has been used for centuries, and research has confirmed the cholesterol - lowering effect of safflower oil. Safflower oil is a source of heart - healthy monounsaturated fats and may also offer other benefits such as reducing blood sugar and improving blood circulation. However, more high - quality human - based research is needed to confirm these potential benefits.


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